Systems Biology

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Systems Biology

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Description

"... Boxed summaries at the start of each subchapter and examples illustrated throughout the book highlight the key points and provide clarity. Most chapters conclude with a short problem set, summarising the basic concepts and prompting further thought. This clear text is a useful starting point for anyone aspiring to solve a biological question using systems biology approaches."
—Phenotype, 2010
Systems biology is a highly topical discipline at the intersection of biochemistry, cell biology, computer science, and systems engineering.
This course book in systems biology is tailored to the needs of advanced students of biology, engineering, and computer science. It has a companion website with solutions to questions in the book, additional chapters, and computer implementations of systems biology models.
The book is a follow-up of the very successful Systems Biology in Practice and incorporates the feedback and suggestions of many lecturers worldwide.
The interdisciplinary team of acclaimed authors have worked closely together to ensure a comprehensive coverage of the topic in a fluent and compelling style.
Further material is available on www.wiley-vch.de/home/systemsbiology
Systems Biology in Practice - Praise from the reviews:
"...this is one book that I bought for myself as soon as it was published."
—British Journal of Occupational Therapy
"This resource does an admirable job of bringing the readers to a level where they can pursue more advanced study and research."
—IEEE Engineering in Medicine and Biology Magazine
"… I am confident that biologists everywhere will benefit from having a copy to hand."
—Theoretical Biology and Medical Modelling

Product Details

Author:	Edda Klipp
Paperback:	592 pages
Publisher:	Wiley-VCH
Publication Date:	August 11, 2009
Language:	English
ISBN:	3527318747
Product Length:	9.5 inches
Product Width:	6.76 inches
Product Height:	1.14 inches
Product Weight:	2.47 pounds
Package Length:	9.4 inches
Package Width:	6.7 inches
Package Height:	1.1 inches
Package Weight:	2.45 pounds
Average Customer Rating:	based on 2 reviews

Customer Reviews

Average Customer Review: 3.0

( 2 customer reviews )
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Most Helpful Customer Reviews

10 of 11 found the following review helpful:

Brilliantly Done Book Jan 08, 2011 By Dr. Terrence McGarty
There are a great number of systems biology texts out there and most are poor attempts to speak to the topic. Their weakness is always that the authors are new to the systems and math parts and they try and just plug together some facts and charts.

This book is an exception. It is a heavy weight but exceptionally well written given it came from a team.

It does a good job on reactions and reaction rates and develops a simple matrix model which is useful. There are times when the pedagogy could be improved but that is a nit. For example the rate equations deal with concentrations of the constituents and for someone approaching this for the first time there is bit an aside comment. For those seeing this as an added text there is no confusion.

There are many real world models worked through so that the reader can see how to apply this.

The level of the mathematics is just right, it is detailed to the point of having reliance on the result but not to the extreme that you lose the biology.

The writing style is superb and one can sit down and use it as a good read, no struggling on where they got something from.

I would have liked to see them work through some cancer pathway models, PTEN and c-MYC, but that is a wish list item.

Overall, this is one of the best if not the best I have seen. There is the book by System Modeling in Cellular Biology: From Concepts to Nuts and Bolts (Bradford Books) which is also exceptionally good, but the Szallasi book shows the signs of many minds. This book is a single presentation, often difficult to do.

7 of 9 found the following review helpful:

Mixture of elaborate words Apr 06, 2011 By Linus
I am a PostDoc in biochemistry and I bought this book very recently. With my all respect to authors, I don't understand to what type of reader this book was dedicated, but my impression that it was not focused on readers at all. First of all, book lacks clarity. It seems that "the interdisciplinary team of acclaimed authors" - thats how they are named at the back front page, collected bunch of elaborate words, put them together and published this book. Does it make book "Systems biology"?
It says that authors worked "closely together to ensure a comprehensive coverage of the topic in a fluent and compelling style". My impression was completely opposite. There is no link between individual chapters at all. Authors tried to cover so many topics, that the result was very brief and sporadic biological topics and at the same time superficial mathematics lacking proper introductions, explanations and coverage. How authors arrive to particular equation and why they are using it for particular biological model is not clear at all. Be sure, in order to understand most of the mathematics presented within you need to have a very solid background built previously and if you have this solid background already, then I am in doubt you will find something useful inside. It is just a sparse collection of various topics without proper focus and discussion.
Is there something positive about the book? I don't know, hard to say, maybe 17.5 section "Tools Compendium", which provides overview of Internet modeling tools.

Would I recommend this book for my friend or colleague? The answer is no.

Thank you for reading,

Linus